Good cop(per), bad cop(per)

Competition in Healthcare: Good, Bad or Ugly?

The role of competition in healthcare is much debated. Despite a wealth of international experience in relation to competition, evidence is mixed and contested and the debate about the potential role for competition is often polarised. This paper considers briefly some of the reasons for this, focusing on what is meant by “competition in healthcare” and why it is more valuable to think about th...

Biological Synthesis of Copper/copper Oxide Nanoparticles

Metal nanoparticles have gained significant interest in the past decade because of their unique physio-chemical properties which has a potential to be used in a wide range of applications. Recent efforts have gained success in synthesising nanoparticles with excellent shape and size control; however they are largely restricted to chemical methods. There is an increasing focus on eco-friendly ‘g...

Studies on copper metabolism. XXXI. Erythrocyte copper.

Copper and Copper Proteins in Parkinson's Disease

Copper is a transition metal that has been linked to pathological and beneficial effects in neurodegenerative diseases. In Parkinson's disease, free copper is related to increased oxidative stress, alpha-synuclein oligomerization, and Lewy body formation. Decreased copper along with increased iron has been found in substantia nigra and caudate nucleus of Parkinson's disease patients. Copper inf...

Role of copper transporters in copper homeostasis.

Copper is a redox active metal that is essential for biological function. Copper is potentially toxic; thus, its homeostasis is carefully regulated through a system of protein transporters. Copper is taken up across the lumen surface of the small intestinal microvilli as cuprous ion by Ctr1. Cupric ion may also be taken up, but those processes are less well understood. Within the cell, intestin...